منابع مشابه
Controlling Rotavirus-associated diarrhea: Could single-domain antibody fragments make the difference?
Group A Rotavirus (RVA) remains a leading cause of severe diarrhea and child mortality. The variable domain of camelid heavy chain antibodies (VHH) display potent antigen-binding capacity, have low production costs and are suitable for oral therapies. Two sets of anti-RVA VHHs have been developed: ARP1-ARP3; 2KD1-3B2. Here, we explore the potential of both sets as a prevention strategy compleme...
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We study the behaviour of iterations of the difference operator δ on streams over {0, 1}. In particular, we show that a stream σ is eventually periodic if and only if the sequence of differences σ, δ(σ), δ(σ), . . ., the ‘δorbit’ of σ as we call it, is eventually periodic. Moreover, we generalise this result to operations δd that sum modulo 2 the elements of each consecutive block of length d +...
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Sera of camelids contain both conventional heterotetrameric antibodies and unique functional heavy (H)-chain antibodies (HCAbs). The H chain of these homodimeric antibodies consists of one antigen-binding domain, the VHH, and two constant domains. HCAbs fail to incorporate light (L) chains owing to the deletion of the first constant domain and a reshaped surface at the VHH side, which normally ...
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When it comes to health risks, sex does matter. Women are twice as likely as men to get multiple sclerosis, rheumatoid arthritis, and migraines. They're also more likely to get cataracts, hepatitis, and thyroid disease. Women experience depression about twice as often as men. And irritable bowel syndrome (IBS) is thought to affect twice as many women as men. Although men have more heart attacks...
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We show that the nonemptiness problem for two-way automata with only one endmarker over unary alphabets is complete for nondeterministic logarithmic space. This should be contrasted with the corresponding problem for two-way automata with two endmarkers, which is known to be NP-complete.
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ژورنال
عنوان ژورنال: Science
سال: 2021
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.abg2294